HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-3-aminopyrrolidine → 3-[3-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-ureido]-pyrrolidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-3-aminopyrrolidine | HCID 2756370 | — |
| Reactant | 4-Nitrophenyl (7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methylcarbamate | HCID 86675769 | — |
| Product | 3-[3-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-ureido]-pyrrolidine-1-carboxylic acid tert-butyl ester | HCID 71209057 | — |
Reaction Steps
3-[3-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-ureido]-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared was prepared starting from intermediate M and 3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester. MS calcd. for C26H30ClN4O4 [(M+H)+] 497.2, obsd. 497.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501732B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-455e7b0545dd46048a972d3a36d3a5e8 |
| Source note | uspto-grants-2013_08 |