HCID 45489844, compound → HCID 71208542, compound

HRID 1887962Notes

Reaction equation

HRID 1887962 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:32])[C:7]([CH2:18][NH:19][C:20](=[O:31])OC3C=CC([N+]([O-])=O)=CC=3)=[CH:8][N:9]2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.[CH2:33]1[CH:38]2[CH2:39][CH:40]3[CH:42]([NH2:43])[C@@H:34]1[CH2:35][C:36]([OH:44])([CH2:41]3)[CH2:37]2>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:32])[C:7]([CH2:18][NH:19][C:20]([NH:43][CH:42]3[CH:34]4[CH2:33][CH:38]5[CH2:37][C:36]([OH:44])([CH2:41][CH:40]3[CH2:39]5)[CH2:35]4)=[O:31])=[CH:8][N:9]2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 45489844HCID 45489844, compoundHCID 866757694-Nitrophenyl (7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methylcarbamate

Product 1

HCID 71208542HCID 71208542, compound

Procedure

1-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-3-(5-hydroxy-adamantan-2-yl)-urea was prepared starting from intermediate M and trans-4-aminoadamantan-1-ol. MS calcd. for C27H29ClN3O3 [(M+H)+] 478.2, obsd. 478.0.

Sources & evidence

ORD record
ord-6dc7ee2c63554786817627d0e68a1859
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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