Methanesulfonyl chloride → HCID 71208218, compound

HRID 1887967Notes

Reaction equation

HRID 1887967 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:29])[C:7]([CH2:18][NH:19][C:20]([NH:22][CH:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]3)=[O:21])=[CH:8][N:9]2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.[CH3:30][S:31](Cl)(=[O:33])=[O:32]>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:29])[C:7]([CH2:18][NH:19][C:20]([NH:22][CH:23]3[CH2:28][CH2:27][N:26]([S:31]([CH3:30])(=[O:33])=[O:32])[CH2:25][CH2:24]3)=[O:21])=[CH:8][N:9]2[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 71208602HCID 71208602, compound

Product 1

HCID 71208218HCID 71208218, compound

Procedure

1-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-3-(1-methanesulfonyl-piperidin-4-yl)-urea was prepared starting from intermediate N and methanesulfonyl chloride. MS calcd. for C23H26ClN4O4S [(M+H)+] 489.1, obsd. 489.1.

Sources & evidence

ORD record
ord-e769a653d09d4000896bb066d9e0fd2a
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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