23138-53-6 → HCID 71208730, compound

HRID 1887976Notes

Reaction equation

HRID 1887976 reaction equation
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:4]=1.[CH3:21][O:22][C:23](=[O:33])[C:24]1[CH:29]=[CH:28][C:27]([N:30]=[C:31]=[O:32])=[CH:26][CH:25]=1>>[CH3:21][O:22][C:23](=[O:33])[C:24]1[CH:25]=[CH:26][C:27]([NH:30][C:31]([NH:1][CH2:2][C:3]2[C:12](=[O:13])[C:11]3[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=3)[N:5]([C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:4]=2)=[O:32])=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 28045423138-53-6HCID 712083983-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-one

Product 1

HCID 71208730HCID 71208730, compound

Procedure

4-[3-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-ureido]-benzoic acid methyl ester was prepared starting from intermediate D and 4-isocyanato-benzoic acid methyl ester. MS calcd. for C25H21ClN3O4 [(M+H)+] 462.1, obsd. 462.0.

Sources & evidence

ORD record
ord-b3d691f0f79a4b7d87a0c25074fc9f5e
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

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