Succinic Acid → HCID 86648413, compound

Participants

Reaction Steps

Succinic acid (1.18 g, dissolved in 35 ml of 2-propanol and 5 ml of water) is slowly added to a solution of Donepezil (3.79 g) in ethyl acetate (70 ml) with stirring at room temperature. The solid precipitated is filtered and dried at 55° C. under vacuum to give the title compound. Melting point: 165.7° C.

Provenance & Evidence