HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic Acid → HCID 86648413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic Acid | HCID 1110 | — |
| Reactant | Donepezil | HCID 3152 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86648413 | HCID 86648413 | — |
Reaction Steps
Donepezil (3.79 g, dissolved in 70 ml of ethyl acetate) is slowly added to a solution of succinic acid (0.59 g) in absolute ethanol (35 ml) with stirring at room temperature. The solid precipitated is filtered and dried at 55° C. under vacuum to give the title compound. Melting point: 169.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501779B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-a9a6ce88f72f4b018c2f35c3bd310b7c |
| Source note | uspto-grants-2013_08 |