HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dihydroxybutanedioic Acid → HCID 86648414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dihydroxybutanedioic Acid | HCID 875 | — |
| Reactant | Donepezil | HCID 3152 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86648414 | HCID 86648414 | — |
Reaction Steps
Tartaric acid (1.5 g, dissolved in 35 ml of 2-propanol-water mixture) is slowly added to a solution of Donepezil (3.79 g) in ethyl acetate (70 ml) with stirring at room temperature. The mixture is stirred for 3 hours at room temperature and concentrated at vacuum to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501779B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-e6e57f14ec02479bb1c2bb882683fe65 |
| Source note | uspto-grants-2013_08 |