HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 11547418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Donepezil | HCID 3152 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 11547418 | HCID 11547418 | — |
Reaction Steps
Sulfuric acid (0.53 ml, dissolved in 35 ml of 2-propanol) is slowly added to a solution of Donepezil (3.79 g) in ethyl acetate (70 ml) with stirring at room temperature. The solid precipitated is filtered and dried at 55° C. under vacuum to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501779B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-bbbcf5ab8445476785a649b4aab7854a |
| Source note | uspto-grants-2013_08 |