Sodium Iodide → HCID 67119962, compound

Participants

Reaction Steps

Anhydrous cerium chloride (0.99 g, 4.0 mmol) and sodium iodide (1.8 g, 12.0 mmol) are added to 10 ml of anhydrous tetrahydrofuran as a solvent to form a suspension. 0.80 g (4.0 mmol) of bromoacetophenone and 0.82 g (4.0 mmol) of N-(2′-methoxyphenyl)-4-piperidone are dissolved into 10 ml of anhydrous tetrahydrofuran, and the solution is added dropwise to the above suspension. Operating according to the post-treatment procedure in General Method three obtains 0.5 g of a white crystal, with yield of 38.5%.

Provenance & Evidence