Sodium Iodide → HCID 67119793, compound

Participants

Reaction Steps

Anhydrous cerium chloride (0.99 g, 4.0 mmol) and sodium iodide (1.8 g of, 12.0 mmol) are added to 10 ml of anhydrous tetrahydrofuran as a solvent to form a suspension. Dissolving 0.97 g (4.0 mmol) of 1-(benzo[d][1,3]dioxol-5-yl)-2-bromoethanone and 0.76 g (4.0 mmol) of N-benzyl-4-piperidone into 10 ml of anhydrous tetrahydrofuran, and the solution is added dropwise to the above suspension and reacting at room temperature for 2 hours. Operating according to the post-treatment procedure in General Method three to obtain 0.70 g of a white crystal, with yield of 42.9%.

Provenance & Evidence