反应详情

温度

50 °C

About 300 g of Resflor® is added over about 1 hour to a stirring solution of about 24 mL of concentrated ammonia in about 3 L of water heated to about 50° C. Additional concentrated ammonia can be added to ensure that the pH is about 9. The mixture is stirred and cooled to room temperature. The resulting precipated Florfenicol is removed by filtration. The filtrate is acidifed to about pH 4.5 with 10% H2SO4 then stirred for about another 1 hour. The resulting precipitated Flunixin is collected by filtration then dried to a moisture content of less than about 1% to yield about 4 g of crude Flunixin (100%).

1. temperaturecooled to room temperature
2. customThe resulting precipated Florfenicol is removed by filtration
3. stirringthen stirred for about another 1 hour
4. customThe resulting precipitated Flunixin
5. filtrationis collected by filtration
6. customthen dried to a moisture content of less than about 1%