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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888229Generated: November 1, 2026

Triethylamine → HCID 178481299, compound

https://huagongshe.com/reaction/1888229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant1-methyl-1H-imidazole-4-sulfonyl chlorideHCID 2736887—
Reactant5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochlorideHCID 178479539—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178481299HCID 17848129960.8%

Reaction Steps

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (0.057 g, 0.17 mmol) was reacted with 1-methylimidazole-4-sulfonyl chloride (0.031 g, 0.17 mmol) in the presence of triethylamine (0.1 mL, 0.71 mmol) and DMAP (0.0021 g, 0.017 mmol) in DMF (3 mL) to give 0.048 g of white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-d3d6531c16214c0f978e2ca0c6014236
Source noteuspto-grants-2013_08