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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888230Generated: November 3, 2026

Triethylamine → HCID 178513523, compound

https://huagongshe.com/reaction/1888230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochlorideHCID 178479539—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178513523HCID 17851352359%

Reaction Steps

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (0.057 g, 0.17 mmol) was reacted with 4-fluorophenyl sulfonyl chloride (0.033 g, 0.17 mmol) in the presence of triethylamine (0.1 mL, 0.71 mmol) and DMAP (0.0021 g, 0.017 mmol) in DMF (3 mL) to give 0.048 g of white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-7998a3c30069454cb6f34850212e8cee
Source noteuspto-grants-2013_08