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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888231Generated: October 29, 2026

Triethylamine → HCID 178504937, compound

https://huagongshe.com/reaction/1888231

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochlorideHCID 178479539—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178504937HCID 17850493713.3%

Reaction Steps

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (0.057 g, 0.17 mmol) was reacted with methanesulfonyl chloride (0.013 mL, 0.17 mmol) in the presence of triethylamine (0.1 mL, 0.71 mmol) and DMAP (0.0021 g, 0.017 mmol) in DMF (3 mL) to give 0.009 g of white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-9f65f74a480a4699bf2ead321d5f6501
Source noteuspto-grants-2013_08