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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888234Generated: November 4, 2026

Triethylamine → HCID 178461036, compound

https://huagongshe.com/reaction/1888234

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant2-Propanesulfonyl chlorideHCID 82408—
Reactant5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochlorideHCID 178479539—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178461036HCID 17846103620.7%

Reaction Steps

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (0.057 g, 0.17 mmol) was reacted with isopropylsulfonyl chloride (0.02 mL, 0.17 mmol) in the presence of triethylamine (0.1 mL, 0.71 mmol) and DMAP (0.0021 g, 0.017 mmol) in DMF (3 mL) to give 0.015 g of a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-a0a31822e819467182c157e2f897c972
Source noteuspto-grants-2013_08