HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Acetylsulfanilyl chloride → HCID 178474287, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Acetylsulfanilyl chloride | HCID 8481 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride | HCID 178479539 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 178474287 | HCID 178474287 | 28% |
Reaction Steps
Following the general procedure of Example 11, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (Example 2) (50 mg, 0.14 mmol), diisopropylethylamine (100 uL, 0.56 mmol), DMAP (25 mg, 0.014 mmol) and 4-(acetylamino)benzenesulfonyl chloride (44 mg, 0.168 mmol) were reacted to give the title compound (20 mg, 28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501780B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-f4cc39587be241d58e517346f6a752b6 |
| Source note | uspto-grants-2013_08 |