HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178433561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1,2-Dimethylimidazole-4-sulfonyl chloride | HCID 2736256 | — |
| Reactant | HCID 178513569 | HCID 178513569 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 178433561 | HCID 178433561 | 27.4% |
Reaction Steps
Following the general procedure of Example 11, 3-(4-piperidinyl)-5-(1H-pyrazol-4-yl)-1H-indazole-7-carboxamide (Example 75) (0.07 mmol), diisopropyl-ethylamine (100 uL, 0.56 mmol), DMAP (25 mg, 0.014 mmol) and 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride (33 mg, 0.17 mmol) were reacted to give the title compound (9 mg, 27% for 3 steps). LC/MS: 469.4 Rt: 1.33 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501780B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-5ee00b7b80ef4986b196315b6bac7b8b |
| Source note | uspto-grants-2013_08 |