HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 178513559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 178513558 | HCID 178513558 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178513559 | HCID 178513559 | 42.5% |
Reaction Steps
The title compound was prepared according to the general procedure of Example 38b. Thus, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-(2-thienyl)-1H-indazole-7-carboxamide (0.076 mmol) in DMF (4 mL) was reacted with K2CO3 (22 mg, 0.16 mmol), sodium iodide (2 mg) and pyrrolidine (26.98 mg, 0.4 mmol) to afford the title compound (16.2 mg, 42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501780B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-f8a66f98565e445d8667025a6234529f |
| Source note | uspto-grants-2013_08 |