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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888272Generated: November 3, 2026

Sodium Iodide → HCID 178513559, compound

https://huagongshe.com/reaction/1888272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantPotassium CarbonateHCID 11430—
ReactantPyrrolidineHCID 31268—
ReactantHCID 178513558HCID 178513558—
SolventDimethylformamideHCID 6228—
ProductHCID 178513559HCID 17851355942.5%

Reaction Steps

The title compound was prepared according to the general procedure of Example 38b. Thus, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-(2-thienyl)-1H-indazole-7-carboxamide (0.076 mmol) in DMF (4 mL) was reacted with K2CO3 (22 mg, 0.16 mmol), sodium iodide (2 mg) and pyrrolidine (26.98 mg, 0.4 mmol) to afford the title compound (16.2 mg, 42%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-f8a66f98565e445d8667025a6234529f
Source noteuspto-grants-2013_08