HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 178483614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 178513558 | HCID 178513558 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178483614 | HCID 178483614 | 38.5% |
Reaction Steps
The title compound was prepared according to the general procedure of Example 38b. Thus, 3-{1-[(3-chloropropyl)sulfonyl]-4-piperidinyl}-5-(2-thienyl)-1H-indazole-7-carboxamide (Example 46a) (0.076 mmol) in DMF (4 mL) was reacted with K2CO3 (22 mg, 0.16 mmol), sodium iodide (2 mg) and dimethyl amine (0.2 mL, 0.4 mmol) to afford the title compound (13.9 mg, 38%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501780B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-54ccce187fd3435c85e090d8bfbd83c8 |
| Source note | uspto-grants-2013_08 |