HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178513533, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,2,2-Trifluoroethanesulfonyl chloride | HCID 74242 | — |
| Reactant | 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride | HCID 178479539 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178513533 | HCID 178513533 | 20.5% |
Reaction Steps
This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (Example 2) (0.030 g, 0.07 mmol) was reacted with 2,2,2-trifluoroethanesulfonyl chloride (0.015 mL, 0.105 mmol) in the presence of triethylamine (0.04 mL, 0.28 mmol) in DMF (2 mL) to give 6.7 mg of white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501780B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-faf9296ad42d4bb7b9fe01a30c4f85e3 |
| Source note | uspto-grants-2013_08 |