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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888294Generated: November 2, 2026

Triethylamine → HCID 178513533, compound

https://huagongshe.com/reaction/1888294

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant2,2,2-Trifluoroethanesulfonyl chlorideHCID 74242—
Reactant5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochlorideHCID 178479539—
SolventDimethylformamideHCID 6228—
ProductHCID 178513533HCID 17851353320.5%

Reaction Steps

This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 5-phenyl-3-(4-piperidinyl)-1H-indazole-7-carboxamide hydrochloride (Example 2) (0.030 g, 0.07 mmol) was reacted with 2,2,2-trifluoroethanesulfonyl chloride (0.015 mL, 0.105 mmol) in the presence of triethylamine (0.04 mL, 0.28 mmol) in DMF (2 mL) to give 6.7 mg of white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501780B2
Source datasetuspto-grants-2013_08
ORD IDord-faf9296ad42d4bb7b9fe01a30c4f85e3
Source noteuspto-grants-2013_08