3-Amino-1-propanol → HCID 178441275, compound

Participants

Reaction Steps

The product from Example 173 and propanolamine (Aldrich) were processed using the method described in Example 178 to afford the title compound. 1H NMR (DMSO-d6) δ 0.48 (s, 3H), 0.90 (t, J=7.3 Hz, 3H), 1.19 (s, 3H), 1.23 (s, 3H), 1.26-1.45 (m, 3H), 1.49-1.57 (m, 2H), 1.57 (s, 9H), 1.57-1.67 (m, 3H), 1.96-2.08 (m, 1H), 2.62-2.68 (m, 3H), 2.72-2.83 (m, 1H), 2.95-3.06 (m, 1H), 3.13-3.26 (m, 1H), 3.37-3.43 (m, 2H), 4.42 (t, J=5.3 Hz, 1H), 7.56 (t, J=5.7 Hz, 1H), 8.50 (s, 1H). (ESI+) m/z 452 (M+H)+. Anal. calcd. for C24H41N3O3S: C, 63.82; H, 9.15; N, 9.30. Found: C, 63.12; H, 8.91; N, 9.25.

Provenance & Evidence