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HRID 1888716생성일: 2026년 10월 25일

Imidazole → 1-(5-{[Tert-butyl(dimethyl)silyl]oxy}-1-benzofuran-2-yl)ethanone

https://huagongshe.com/reaction/1888716

반응식

참여 물질

역할이름HCID투입량
반응물ImidazoleHCID 795—
반응물tert-Butyldimethylsilyl chlorideHCID 28928—
반응물1-(5-Hydroxy-1-benzofuran-2-yl)ethanoneHCID 3237877—
용매DimethylformamideHCID 6228—
생성물1-(5-{[Tert-butyl(dimethyl)silyl]oxy}-1-benzofuran-2-yl)ethanoneHCID 5804749898%

반응 단계

Using 1-(5-hydroxy-1-benzofuran-2-yl)ethanone (1.15 g, 6.53 mmol), DMF (10 mL), tert-butyldimethylchlorosilane (1.07 g, 7.18 mmol) and imidazole (666 mg, 9.80 mmol), an operation in the same manner as in Reference Example 16 was performed to give the title compound (1.76 g, yield 98%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08501804B2
출처 데이터셋uspto-grants-2013_08
ORD IDord-a4c90fe9f12449ae9ac57b8666de2454
출처 메모uspto-grants-2013_08