Sodium sulfate decahydrate → HCID 58047668, compound

Participants

Reaction Steps

To a suspension of lithium aluminum hydride (59.6 mg, 1.57 mmol) in THF (7 mL) was added dropwise a solution of methyl 2-[1-(acetylamino)ethyl]-1,3-benzothiazole-6-carboxylate (220 mg, 0.785 mmol) obtained in Reference Example 84 in THF (5 mL) under ice-cooling, and the mixture was stirred for 30 min. After completion of the reaction, sodium sulfate decahydrate (760 mg) was slowly added thereto, and the mixture was filtered through celite. The filtrate was concentrated under reduced pressure, and the obtained residue was triturated with diisopropyl ether to give the title compound (142 mg, yield 73%).

Provenance & Evidence