反应详情

A solution of 5-bromopyridin-2-ol (5.22 g, 30.0 mmol) and N-iodosuccinimide (7.42 g, 33.0 mmol) in acetonitrile (150 mL) was heated under reflux under a nitrogen atmosphere for 1 hr. After being allowed to cool to room temperature, the resulting solid was collected and washed with acetonitrile to give the title compound (7.07 g, yield 79%).

1. temperatureunder reflux under a nitrogen atmosphere for 1 hr
2. customthe resulting solid was collected
3. washwashed with acetonitrile