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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888863Generated: November 3, 2026

HCID 67278842, compound → HCID 58916222, compound

https://huagongshe.com/reaction/1888863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67278842HCID 67278842—
CatalystPalladium hydroxideHCID 9942167—
SolventMeOH tetrahydrofuranHCID 21899815—
ProductHCID 58916222HCID 58916222—

Reaction Steps

In analogy to example 3 step 5 with 22 mg succinic acid 4-{4-[(5S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-1-(6-carboxy-8-cyclopropyl-3-fluoro-5-oxo-5,8-dihydro-[1,8]naphthyridin-2-yl)-piperidin-4-yl ester benzyl ester (MW: 817.80, 0.026 mmol) and 2 mg of palladium hydroxide 20% on activated carbon in 20 ml of a 1/1 tetrahydrofuran/methanol mixture. Yield: 16 mg, 81%. MS: 729 (M+H)+, 727 (M+H)−, Method ESI+, ESI−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501774B2
Source datasetuspto-grants-2013_08
ORD IDord-abb9c99514d643e28abe4fedbb7e756e
Source noteuspto-grants-2013_08