HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Bicyclo[2.2.2]octane-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Bicyclo(2.2.2)octan-2-one | HCID 137688 | — |
| Product | Bicyclo[2.2.2]octane-2,3-dione | HCID 548936 | — |
Reaction Steps
In analogy to Example 1 Step B]: from bicyclo[2.2.2]octan-2-one, 1.416 g, (synthesis: JOC., 1993, 58, 7622), SeO2 (2.218 g) in acetic acid (8 ml) on heating at 130° C. for 12 h, purification of the crude product by flash chromatography (heptane/AcOEt 100-75%), there was obtained bicyclo[2.2.2]octane-2,3-dione (0.396 g) as yellow solid. MS (ESI): 156 (M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501940B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-199435193ae1476cb6a7850f39f55f90 |
| Source note | uspto-grants-2013_08 |