HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → (5r,8s)-8,9,9-Trimethyl-3-[(1-methylcyclopropyl)methyl]-5,6,7,8-tetrahydro-5,8-methanocinnoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | (+)-Camphorquinone | HCID 1549179 | — |
| Reactant | [3-(1-Methyl-cyclopropyl)-2-oxo-propyl]-phosphonic acid dim ethyl ester | HCID 86638118 | — |
| Product | (5r,8s)-8,9,9-Trimethyl-3-[(1-methylcyclopropyl)methyl]-5,6,7,8-tetrahydro-5,8-methanocinnoline | HCID 67071999 | — |
Reaction Steps
Light-yellow solid MS (ESI): 257.1 (MH+). Prepared from (1S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptane-2,3-dione (commercially available), [3-(1-methyl-cyclopropyl)-2-oxo-propyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501940B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-36c4a9760a834170915e5152c136bcdd |
| Source note | uspto-grants-2013_08 |