HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 3-[4-Fluoro-2-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydro-5,8-ethanocinnoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Bicyclo[2.2.2]octane-2,3-dione | HCID 548936 | — |
| Reactant | [2-(4-Fluoro-2-trifluoromethyl-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester | HCID 86609939 | — |
| Product | 3-[4-Fluoro-2-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydro-5,8-ethanocinnoline | HCID 46175330 | — |
Reaction Steps
White solid MS (ESI): 323.1 (MH+). Prepared from bicyclo[2.2.2]octane-2,3-dione, [2-(4-fluoro-2-trifluoromethyl-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501940B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-a71b0c671afc404eb8c29d8627a6300c |
| Source note | uspto-grants-2013_08 |