3,4,5-Trimethoxybenzaldehyde → HCID 178492111, compound

HRID 1888949Notes

Reaction equation

HRID 1888949 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[NH:9][C:10](=[O:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:25]=[C:26]([O:30][CH3:31])[C:27]=1[O:28][CH3:29])[CH:23]=O>CO>[CH3:8][C:5]1[CH:6]=[CH:7][C:2](/[N:1]=[CH:23]/[C:22]2[CH:25]=[C:26]([O:30][CH3:31])[C:27]([O:28][CH3:29])=[C:20]([O:19][CH3:18])[CH:21]=2)=[C:3]([NH:9][C:10](=[O:17])[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:4]=1

Participants

4

Reactant 2

HCID 68583,4,5-TrimethoxybenzaldehydeHCID 68519552N-(2-amino-5-methylphenyl)benzamide

Product 1

HCID 178492111HCID 178492111, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of N-(2-amino-5-methylphenyl)benzamide (2 mmol) and 3,4,5-trimethoxybenzaldehyde (3 mmol) in methanol was stirred at room temperature for 12 h. The suspension was filtered and the solid was washed with methanol to afford (E)-N-(5-methyl-2-(3,4,5-trimethoxybenzylideneamino)phenyl)benzamide as a yellow solid.

Workup

  1. filtrationThe suspension was filtered
  2. washthe solid was washed with methanol

Sources & evidence

ORD record
ord-86009dd0171e45e39284ab45b480b69c
Source dataset
uspto-grants-2013_08
Patent number
US08501957B2

Reaction notes

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