Dimethylformamide → HCID 178484361, compound

Participants

Reaction Steps

A mixture of 1,1-dimethylethyl 3-(aminocarbonothioyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate (I112) (99 mg, 0.349 mmol) in N,N-dimethylformamide (DMF) dimethyl acetal (3 ml, 22.41 mmol) was stirred at room temperature for 1 h. The mixture became red/orange and never went to a clear solution. The DMF dimethyl acetal was evaporated and the product triturated with ether to give an orange solid of desired product in 118 mg.

Provenance & Evidence