Azobisisobutyronitrile → HCID 59351659, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-[(2-methoxyethoxy)methyl]-3-(4′-methylbiphenyl-2-yl)-1,2,4-oxadiazol-5(4H)-one (46.6 g), N-bromosuccinimide (26.9 g), α,α′-azobisisobutyronitrile (2.2 g) and carbon tetrachloride (500 mL) was stirred at 80° C. for 6 hr. Insoluble material was filtered off, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography to give the title compound as colorless oil (30.5 g, 53%).

Provenance & Evidence