Trifluoroacetate → HCID 178526710, compound

HRID 1890288Notes

Reaction equation

HRID 1890288 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C@H:9]2[CH2:14][CH2:13][C@H:12]([OH:15])[CH2:11][CH2:10]2)[C:5]([N+:16]([O-:18])=[O:17])=[CH:4][CH:3]=1.FC(F)(F)C([O-])=[O:22]>>[OH:15][C@H:12]1[CH2:13][CH2:14][C@H:9]([NH:8][C:6]2[N:7]=[C:2]([OH:22])[CH:3]=[CH:4][C:5]=2[N+:16]([O-:18])=[O:17])[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 84468TrifluoroacetateHCID 178526633HCID 178526633, compound

Product 1

HCID 178526710HCID 178526710, compound

Procedure

From trans-4-(6-chloro-3-nitropyridin-2-ylamino)cyclohexanol, trifluoroacetate, prepared in a similar manner as the one described in Example 1.3, Step B, the title compound was obtained. LCMS m/z=254.4 [M+H]+.

Sources & evidence

ORD record
ord-bfd49c3feacf4b9388f08dafe87c9e1b
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

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