2-Chlorocyclohexanone → 2-(5-(Benzyloxy)-3H-imidazo[4,5-b]pyridin-3-yl)cyclohexanone

HRID 1890289Notes

Reaction equation

Cl[CH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[O:8].[CH2:9]([O:16][C:17]1[N:22]=[C:21]2[NH:23][CH:24]=[N:25][C:20]2=[CH:19][CH:18]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([O:16][C:17]1[N:22]=[C:21]2[N:23]([CH:2]3[CH2:7][CH2:6][CH2:5][CH2:4][C:3]3=[O:8])[CH:24]=[N:25][C:20]2=[CH:19][CH:18]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

Reactant 2

HCID 132032-Chlorocyclohexanone

HCID 178420377HCID 178420377, compound

Product 1

HCID 673135802-(5-(Benzyloxy)-3H-imidazo[4,5-b]pyridin-3-yl)cyclohexanone

Procedure

From 2-chlorocyclohexanone and 5-(benzyloxy)-3H-imidazo[4,5-b]pyridine, prepared in a similar manner as the one described in Example 1.1, Step C, the title compound was obtained. LCMS m/z=322.2 [M+H]+.

Sources & evidence

ORD record: ord-57dea30b2c464d67ae4bbd80e6dfe5e1
Source dataset: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08507473B2

Reaction notes

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