(4-Fluoro-2-methylphenyl)boronic acid → HCID 178427854, compound

HRID 1890301Notes

Reaction equation

HRID 1890301 reaction equation
C([O:8][C:9]1[N:14]=[C:13]2[NH:15][CH:16]=[N:17][C:12]2=[CH:11][CH:10]=1)C1C=CC=CC=1.[F:18][C:19]1[CH:24]=[CH:23][C:22](B(O)O)=[C:21]([CH3:28])[CH:20]=1>>[F:18][C:19]1[CH:24]=[CH:23][C:22]([N:15]2[C:13]3=[N:14][C:9]([OH:8])=[CH:10][CH:11]=[C:12]3[N:17]=[CH:16]2)=[C:21]([CH3:28])[CH:20]=1

Participants

3

Reactant 2

HCID 2734665(4-Fluoro-2-methylphenyl)boronic acidHCID 178420377HCID 178420377, compound

Product 1

HCID 178427854HCID 178427854, compound

Procedure

From 5-(benzyloxy)-3H-imidazo[4,5-b]pyridine and 4-fluoro-2-methylphenylboronic acid, prepared in a similar manner as the one described in Example 1.26, the title compound was obtained. LCMS m/z=244.0 [M+H]+.

Sources & evidence

ORD record
ord-30e8b17a40294411a7dfa43dcdcb3a35
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

Loading…