2-Fluoro-3-(trifluoromethyl)benzeneboronic acid → HCID 178515767, compound

HRID 1890313Notes

Reaction equation

HRID 1890313 reaction equation
C([O:8][C:9]1[N:14]=[C:13]2[NH:15][CH:16]=[N:17][C:12]2=[CH:11][CH:10]=1)C1C=CC=CC=1.[F:18][C:19]1[C:24]([C:25]([F:28])([F:27])[F:26])=[CH:23][CH:22]=[CH:21][C:20]=1B(O)O>>[F:18][C:19]1[C:24]([C:25]([F:26])([F:27])[F:28])=[CH:23][CH:22]=[CH:21][C:20]=1[N:15]1[C:13]2=[N:14][C:9]([OH:8])=[CH:10][CH:11]=[C:12]2[N:17]=[CH:16]1

Participants

3

Reactant 2

HCID 162171692-Fluoro-3-(trifluoromethyl)benzeneboronic acidHCID 178420377HCID 178420377, compound

Product 1

HCID 178515767HCID 178515767, compound

Procedure

From 5-(benzyloxy)-3H-imidazo[4,5-b]pyridine and 2-fluoro-3-(trifluoromethyl)phenylboronic acid, prepared in a similar manner as the one described in Example 1.26, the title compound was obtained. LCMS m/z=298.1 [M+H]+.

Sources & evidence

ORD record
ord-e7540db49a1b49b1805979b0dd004a72
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

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