2-Bromo-6-fluorobenzotrifluoride → HCID 178515757, compound

HRID 1890325Notes

Reaction equation

HRID 1890325 reaction equation
C([O:8][C:9]1[N:14]=[C:13]2[NH:15][CH:16]=[N:17][C:12]2=[CH:11][CH:10]=1)C1C=CC=CC=1.[Br:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21](F)[C:20]=1[C:26]([F:29])([F:28])[F:27]>>[Br:18][C:19]1[C:20]([C:26]([F:27])([F:28])[F:29])=[C:21]([N:15]2[C:13]3=[N:14][C:9]([OH:8])=[CH:10][CH:11]=[C:12]3[N:17]=[CH:16]2)[CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 27733452-Bromo-6-fluorobenzotrifluorideHCID 178420377HCID 178420377, compound

Product 1

HCID 178515757HCID 178515757, compound

Procedure

From 5-(Benzyloxy)-3H-imidazo[4,5-b]pyridine and 1-bromo-3-fluoro-2-(trifluoromethyl)benzene, prepared in a similar manner as the one described in Example 1.96, the title compound was obtained. LCMS m/z=358.0 [M+H]+.

Sources & evidence

ORD record
ord-2c8924aa5b5948a38eeac8b7b726b03d
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

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