HCID 178422448, compound → HCID 178425384, compound

Participants

Reaction Steps

To a solution of 3-(4-bromo-5-chloro-2-methylphenyl)-3H-imidazo[4,5-b]pyridin-5-ol (320 mg, 0.95 mmol) in MeOH (8.0 mL) was added palladium hydroxide (20% on carbon, 65 mg). The mixture was placed in a Parr shaker under H2 (30 psi) for 12 h, filtered through Celite® and concentrated. The mixture was purified by preparative HPLC to give the title compound as a white solid. LCMS m/z=260.1, [M+H]+.

Provenance & Evidence