Trimethyl orthobeznoate → HCID 178515744, compound

HRID 1890340Notes

Reaction equation

HRID 1890340 reaction equation
C([O:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:12]([NH2:22])=[CH:11][CH:10]=1)C1C=CC=CC=1.CO[C:25](OC)(OC)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[C:26]1([C:25]2[N:15]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[C:13]3=[N:14][C:9]([OH:8])=[CH:10][CH:11]=[C:12]3[N:22]=2)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 69720Trimethyl orthobeznoateHCID 67312740HCID 67312740, compound

Product 1

HCID 178515744HCID 178515744, compound

Procedure

From 6-(benzyloxy)-N2-phenylpyridine-2,3-diamine and trimethyl orthobenzoate, prepared in a similar manner as the one described in Example 1.117, the title compound was obtained as a white solid. 1H NMR (400 MHz, DMSO-d6) δ ppm 6.61 (d, J=8.3 Hz, 1H), 7.29-7.57 (m, 10H), 8.00 (d, J=8.6 Hz, 1H), 11.07 (broad s, 1H).

Sources & evidence

ORD record
ord-c00b8597616f4b46b36039a58504a350
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

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