Tert-butyl 3-iodoazetidine-1-carboxylate → HCID 25069923, compound

HRID 1890369Notes

Reaction equation

HRID 1890369 reaction equation
I[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:19]=[CH:18][C:17]([C:20]3[O:24][CH:23]=[N:22][CH:21]=3)=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH:6]=[CH:5]2.[C:25]([O:29][C:30]([N:32]1[CH2:35][CH:34](I)[CH2:33]1)=[O:31])([CH3:28])([CH3:27])[CH3:26]>>[C:25]([O:29][C:30]([N:32]1[CH2:35][CH:34]([C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[N:7]([S:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]4[O:24][CH:23]=[N:22][CH:21]=4)=[CH:16][CH:15]=2)(=[O:12])=[O:13])[CH:6]=[CH:5]3)[CH2:33]1)=[O:31])([CH3:28])([CH3:26])[CH3:27]

Participants

3

Reactant 2

HCID 11000522Tert-butyl 3-iodoazetidine-1-carboxylateHCID 68596862HCID 68596862, compound

Product 1

HCID 25069923HCID 25069923, compound

Procedure

This compound was prepared from 5-Iodo-1-(4-oxazol-5-yl-benzenesulfonyl)-1H-indole and 3-iodoazetidin-1-carboxylic acid tert-butyl ester by the method outlined under 1.b). ESI-MS [m/z]: 380.05 [M-Boc-+H]+.

Sources & evidence

ORD record
ord-cc898fd6034344c6b1b53fe0173ba58b
Source dataset
uspto-grants-2013_08
Patent number
US08507469B2

Reaction notes

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