HCID 25074324, compound → HCID 25069606, compound

HRID 1890372Notes

Reaction equation

HRID 1890372 reaction equation
[NH:1]1[CH2:4][CH:3]([C:5]2[CH:6]=[C:7]3[C:11](=[CH:12][CH:13]=2)[N:10]([S:14]([C:17]2[CH:22]=[CH:21][C:20]([C:23]4[O:27][CH:26]=[N:25][CH:24]=4)=[CH:19][CH:18]=2)(=[O:16])=[O:15])[CH:9]=[CH:8]3)[CH2:2]1.Cl.N1CC(C2C=C3C(=CC=2)N(S(C2C=CC=CC=2)(=O)=O)CC3)C1>>[NH:1]1[CH2:2][CH:3]([C:5]2[CH:6]=[C:7]3[C:11](=[CH:12][CH:13]=2)[N:10]([S:14]([C:17]2[CH:18]=[CH:19][C:20]([C:23]4[O:27][CH:26]=[N:25][CH:24]=4)=[CH:21][CH:22]=2)(=[O:16])=[O:15])[CH2:9][CH2:8]3)[CH2:4]1

Participants

3

Reactant 2

HCID 25074324HCID 25074324, compoundHCID 131730800HCID 131730800, compound

Product 1

HCID 25069606HCID 25069606, compound

Procedure

This compound was prepared from 5-azetidin-3-yl-1-(4-oxazol-5-yl-benzensulfonyl)-1H-indole by the method outlined for compound 7. ESI-MS [m/z]: 382.05 [M+H]+. 1H-NMR (400 MHz, d6-DMSO): δ=8.7 (bs, 1H), 8.55 (s, 1H), 7.9 (m, 5H), 7.45 (d, 1H), 7.25 (s, 1H), 7.2 (d, 1H), 4.2 (m, 2H), 4.1-3.9 (m, 5H), 2.95 ppm (t, 3H).

Sources & evidence

ORD record
ord-2f5ffc6e98574f549d683204c6d95fb4
Source dataset
uspto-grants-2013_08
Patent number
US08507469B2

Reaction notes

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