(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine → 1-(Thieno[3,2-c]pyridin-2-yl)ethan-1-amine

HRID 1890520노트

반응식

HRID 1890520 반응식
Cl.[S:2]1[C:10]2[CH:9]=[CH:8][N:7]=[CH:6][C:5]=2[CH:4]=[C:3]1[CH2:11][NH2:12].S1C2C=CN=CC=2C=[C:14]1C(O)C.N1C2=NC=CC=C2C(CN)=C1>>[S:2]1[C:10]2[CH:9]=[CH:8][N:7]=[CH:6][C:5]=2[CH:4]=[C:3]1[CH:11]([NH2:12])[CH3:14]

참가 물질

4

반응물 3

HCID 17959419(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamineHCID 673049441-(Thieno[3,2-c]pyridin-2-yl)ethan-1-olHCID 67306703Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride

생성물 1

HCID 669661661-(Thieno[3,2-c]pyridin-2-yl)ethan-1-amine

실험 절차

Intermediate D′ was prepared from 1-(thieno[3,2-c]pyridin-2-yl)ethanol (D′-4) following similar procedures for synthesizing intermediate A from A-3, as described above.

출처 및 근거

ORD 기록
ord-8949dea0ce0644ed867a6861f74ae0d6
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08507487B2

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