(1H-Thieno[3,2-c]pyrazol-5-yl)methanol → (1H-Thieno[3,2-c]pyrazol-5-yl)methanaminium chloride

HRID 1890527Notes

Reaction equation

HRID 1890527 reaction equation
[NH:1]1[C:5]2[CH:6]=[C:7]([CH2:9]O)[S:8][C:4]=2[CH:3]=[N:2]1.[ClH:11].S1C2C=C[N:17]=CC=2C=C1CN>>[Cl-:11].[NH:1]1[C:5]2[CH:6]=[C:7]([CH2:9][NH3+:17])[S:8][C:4]=2[CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 57354336(1H-Thieno[3,2-c]pyrazol-5-yl)methanolHCID 67306703Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride

Product 1

HCID 86671432(1H-Thieno[3,2-c]pyrazol-5-yl)methanaminium chloride

Procedure

Intermediate F was prepared from (1H-thieno[3,2-c]pyrazol-5-yl)methanol (F-6) following similar procedures for synthesizing intermediate D from D-3, as described above.

Sources & evidence

ORD record
ord-f401d5b9f9254df9a05d4faad24d9ce9
Source dataset
uspto-grants-2013_08
Patent number
US08507487B2

Reaction notes

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