HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1H-Pyrrolo[2,3-b]pyridin-2-yl)methanamine → (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1H-Pyrrolo[2,3-b]pyridin-2-yl)methanamine | HCID 67305381 | — |
| Reactant | Methyl 1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate | HCID 67306524 | — |
| Reactant | Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride | HCID 67306703 | — |
| Product | (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)methanamine | HCID 67306119 | — |
Reaction Steps
Intermediate H′ was prepared from methyl 1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (H′-1) following similar procedures for synthesizing intermediate D from D-2, as described above. MS (m/z): 278 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507487B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-ae4b69bc47484503aff0fff367f26e3e |
| Source note | uspto-grants-2013_08 |