HCID 67305210, compound → (1,5-Naphthyridin-2-YL)methanamine

HRID 1890589Notes

Reaction equation

HRID 1890589 reaction equation
[N:1]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11]O.Cl.S1C2C=C[N:19]=CC=2C=C1CN>>[N:1]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][NH2:19]

Participants

3

Reactant 2

HCID 67305210HCID 67305210, compoundHCID 67306703Thieno[3,2-c]pyridin-2-ylmethanamine hydrochloride

Product 1

HCID 67304940(1,5-Naphthyridin-2-YL)methanamine

Procedure

Intermediate 8 was prepared from (1,5-naphthyridin-2-yl)methanol (8-4) following the procedures similar to the procedure for synthesizing intermediate D from D-3. MS (m/z): 160 (M+1)+.

Sources & evidence

ORD record
ord-b7c26d161d024101b4cfe4fac7c857cd
Source dataset
uspto-grants-2013_08
Patent number
US08507487B2

Reaction notes

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