HCID 23156127, compound → HCID 69435197, compound

Participants

Reaction Steps

[4-(2-Ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)phenyl]phenylmethylazide (0.580 g, 1.46 mmol) obtained in Step 1 was dissolved in ethanol (30 mL), and the flask was filled with argon. 10% Palladium-carbon (50% wet, 0.311 g) was added to the solution, followed by stirring for 6 hours under hydrogen atmosphere. The unsoluble material was filtered out through Celite, and washed with ethanol. The filtrate was combined and concentrated under reduced pressure. The residue was crystallized from diisopropyl ether-hexane to obtain Compound 4 (0.510 g, yield 94%).

Provenance & Evidence