HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl 4-bromobenzimidate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Product | Ethyl 4-bromobenzimidate hydrochloride | HCID 19017302 | 99% |
Reaction Steps
A solution of 4-bromobenzonitrile (17.65 g, 97 mmol) in ethanol (500 mL) was acidified with hydrogen chloride gas at 0° C. for fifteen minutes. The solution was allowed to stir for 16 h. The solution was condensed under reduced pressure to afford the title compound (25.35 g, 99%). MS (ESI) m/z 228.1 [M]+, 230.4 [M+2]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507492B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-3b007993abcb4c4e9830020366af38b9 |
| Source note | uspto-grants-2013_08 |