Benzene, 1-(bromomethyl)-3-nitro- → 1-(Methanesulfonylmethyl)-3-nitrobenzene

Participants

Reaction Steps

To a solution of 1-bromomethyl-3-nitro-benzene (5.0 g, 23 mmol) in ethanol (50 mL) was added solution of sodium methanesulfinate (3.06 g, 30 mmol) in ethanol (30 mL) and the mixture was stirred for 4 h at room temperature, then was concentrated in vacuo to volume about 20 mL and diluted with water (200 mL). Formed precipitate was filtered out, washed with water (2×100 mL) and dried to give 1-methanesulfonylmethyl-3-nitro-benzene (4.3 g; 87%) as yellowish crystalline powder.

Provenance & Evidence