1-(Methanesulfonylmethyl)-3-nitrobenzene → 3-(Methanesulfonylmethyl)aniline

Participants

Reaction Steps

1-Methanesulfonylmethyl-3-nitro-benzene (4.3 g; 20 mmol) was hydrogenated over Raney nickel (0.5 g) in methanol at 50° C. and 70 psi for 4 h. The catalyst was filtered out, washed with warm methanol, and the combined filtrates were evaporated to give 3.33 g (90%) of 3-methanesulfonylmethyl-phenylamine as colorless solid.

Provenance & Evidence