HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → 2-Amino-5-phenylfuran-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | 2-Amino-4,5-diphenyl-3-furonitrile | HCID 389699 | — |
| Product | 2-Amino-5-phenylfuran-3-carbonitrile | HCID 693961 | 38% |
Reaction Steps
2 was prepared in 38% yield from 2-bromo acetophenone (1), similar to 2-amino-4,5-diphenylfuran-3-carbonitrile (see Example 5 above). 1H NMR (300 MHz, CDCl3) δ 7.50-7.47 (m, 2H), 7.39-7.33 (m, 2H), 7.27-7.25 (m, 1H), 6.54 (s, 1H), 4.86 (br, 2H). LCMS (ESI) m/z 185.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507502B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-2c38911d98074961bb663487e5e39e6e |
| Source note | uspto-grants-2013_08 |