Diisopropyl Ether → (4-Aminophenyl)(imino)methyl-lambda6-sulfanone

Participants

Reaction Steps

A solution of 2.45 g (12.2 mmol) of (RS)—S-(4-nitrophenyl)-S-methyl sulfoximide in 150 ml of ethanol is hydrogenated at room temperature with use of 0.80 g of Pd/C (10%×50% H2O) under a hydrogen atmosphere at normal pressure over 4 hours. The hydrogen absorption is 920 ml. The batch is filtered and concentrated by evaporation. The residue that is obtained is digested with diisopropyl ether. 1.90 g (11.2 mmol, corresponding to 92% of theory) is obtained.

Provenance & Evidence